Yujie Shi

Research Associate, Ph.D.

School of Pharmaceutical Sciences, Peking University

E-mail: yujiestone@bjmu.edu.cn

Address：Department of pharmaceutical analysis, School of Pharmacertical Sciences, Peking University,38 Xueyuan Rd, Haidian District, Beijing 100191, China

Education

●2013-2016 School of Pharmaceutical Sciences, Peking University Ph.D.

● 2002-2005 School of Pharmaceutical Sciences, Peking University M.S.

● 1995-1999 School of Pharmaceutical Sciences, China Pharmaceutical University B.S.

Working Experience

● 2025- School of Pharmaceutical Sciences, Peking University Research Associate

● 2018-2020 School of Engineering and Applied Sciences, Harvard University Visiting scholar

● 2007-2025 School of Pharmaceutical Sciences, Peking University Lecture ● 2005-2007 School of Pharmaceutical Sciences, Peking University Teaching assistant

Research Interests

● Construction and Application of Novel Drug Delivery Systems for Hydrophobic Drugs and Biomacromolecules

● Exploration of New methodologies and Technologies for Pharmaceutical Analysis

Selected Publications

1. Shi, Yujie#*, Ningning Shi#, Yuelin Yang#, Zhetao Zheng and Qing Xia*. Unnatural Amino Acid-Based Ionic Liquid Enables Oral Treatment of Nonsense Mutation Disease in Mice. Advanced science, 2024, 11(13):2306792.

2. An Lu#, Kang Du#, Meng Wang#, Zehang Zhu, Lei Lei, Yujie Shi*. Natural endogenous material-based vehicles for delivery of macromolecular drugs. Chinese Journal of Natural Medicines. 2024, 22(12):1163-1176.

3. He Wei*, Shi Yujie*, Ding Qu*. Natural-derived drug carriers (NDDCs) for precision therapy [J]. Chinese Journal of Natural Medicines, 2024, 23(0): 1-2.

4. Yujie Shi*, Xiaona Li. (2023). High-Performance Liquid Chromatography Coupled with Tandem Mass Spectrometry Method for the Identification and Quantification of Lipids in Liposomes. In: D'Souza, G.G., Zhang, H. (eds) Liposomes. Methods in Molecular Biology, vol 2622. Humana, New York, NY.

5. Lin Zhai#, Yujie Shi#, Yi Yan, An Lu, Xiaoyu Liu, Lei Lei, Yi Sun, Linxia Jiang, Xiangyu Wang, Honggang Qian*, Jiancheng Wang*. Local sustained release of PD-1 monoclonal antibody and lenvatinib by thermo-sensitive hydrogel for improving tumor immunotherapy. Chinese Chemical Letters, 2023, 34(8):108104.

6. Linxia Jiang, Yi Sun, An Lu, Xiangyu Wang, Yujie Shi*. Ionic liquids: promising approach for oral drug delivery. Pharmaceutical Research, 2022, 39(10):2353-2365,

7. Yujie Shi#, An Lu#, Xiangyu Wang, Zakia Belhadja, Jiancheng Wang*, Qiang Zhang*. A review of existing strategies for designing long-acting parenteral formulations: focus on underlying mechanisms, and future perspectives. Acta Pharmaceutica Sinica B, 2021, 11(8):2396-2415.

8. Yujie Shi, Zongmin Zhao, Yongsheng Gao, Daniel C. Pan, Alyssa K. Salinas, Eden E.L. Tanner, Junling Guo, Samir Mitragotri*. Oral delivery of sorafenib through spontaneous formation of ionic liquid nanocomplexes. Journal of Controlled Release, 2020, 322: 602-609.

9. Yujie Shi, Zongmin Zhao, Kevin Peng, Yongsheng Gao, Debra Wu, Jayoung Kim, Samir Mitragotri*. Enhancement of Anticancer Efficacy and Tumor Penetration of Sorafenib by Ionic Liquids. Advanced Healthcare Materials, 2020, 10(2):2001455.

10. Yujie Shi#, Dong Peng#, Dan Wang, Zongmin Zhao, Binlong Chen, Bing He, Yukun Zhu, Kun Wang, Jie Tian*, Qiang Zhang*. Biodistribution Survey of Oxidized Single-Wall Carbon Nanohorns Following Different Administration Routes by Using Label-Free Multispectral Optoacoustic Tomography. International Journal of Nanomedicine, 2019, 14:9809-9821.

11. Yujie Shi, Zujin Shi, Suxin Li, Yuan Zhang, Bing He, Dong Peng, Jie Tian, Ming Zhao*, Xueqing Wang *, Qiang Zhang. The interactions of single-wall carbon nanohorns with polar epithelium. International Journal of Nanomedicine, 2017, 12:4177-4194.